The dynamic nature of preschool autism

peopleAutism currently remains a diagnosis based exclusively on observed behaviours and analysis of developmental history. Although various early diagnostic markers have been put forward as potential candidates to make the diagnostic process more objective and onwards remove the subjectivity behind making a diagnosis, none have so far lived up to expectation.

Part of the reason for the desire for early biomarkers rests on the perceived effectiveness of early intervention, very early intervention, and how a universal biological or genetic marker would inevitably further inform about the aetiology of autism.

The notion of an objective marker for autism is however complicated. Not only because of the heterogeneity which exists with regards to the presentation of autism, but also following moves to classify autism as a more plural condition (‘the autisms’), the growing interest in the process of regression in cases of autism and the complicating factor of comorbidity which often follows a diagnosis of autism. That also the presentation of autism may be prone to some instability during the early years of development and beyond is also another interfering variable.

The paper by Hedvall and colleagues* adds to a growing volume of research literature suggesting that the presentation of autism in the preschool years may be surprisingly unstable; urging caution when it comes to drawing too many conclusions about the nature of autism in early infancy. Based on observations of 208 preschool children with various types of diagnosis/presentation included under the autism spectrum umbrella, researchers charted the developmental trajectories of participants over two years. They looked at the presentation of autism symptoms as well as other important factors such as the presence of intellectual disability.

Their results suggested that the presentation of autism and associated developmental skills during this important early developmental period was a surprisingly fluid process. In particular, around half of children at the follow-up point were reported to present with some degree of intellectual disability, mostly severe intellectual disability alongside their autism. This contrasted sharply with little or no mention of such issues at first diagnostic encounter.

On that basis, researchers conclude that assessments made later in childhood, prior to the start of school, may offer a more reliable picture of the presentation of autism and associated issues compared with an earlier preschool assessment.

Further work is required on this topic area to further confirm how much and for whom stability might be an issue when it comes to the presentation of autism and associated issues. Whether such findings also translate into biological or genetic expression changes as a function of maturation is as yet unknown, as is the relative contribution of any early intervention measures which participants may have been following during the interval period. What is clear is that autism is a dynamic condition; and outside a need to show how autism ages with a person, the early days presentation of autism remains an important research topic.

* Hedvall A. et al. Autism and developmental profiles in preschoolers: stability and change over time. Acta Paediatr. 2013 Oct 8. doi: 10.1111/apa.12455.

Further commentary on this study can be found at:

Click here for reuse options!
Copyright 2018 Autism Daily Newscast

Top Stories and Breaking News

Researchers hope to revolutionize autism diagnosis through Autism & Beyond app

New York — A team of researchers from Duke are hoping to revolutionize how autism is diagnosed in young children through an iPhone app called ‘Autism & Beyond’. The researchers are working closely with Apple in hopes of improving how autism is diagnosed in children today. Due to the surge of the number of children […]

The damage of Chlorine Dioxide also peddled as Miracle Mineral Solution

For those of you that do not know there’s a very real threat to our autistic children in the world today. Naive parents and carers are being told that parasitic worms are the cause of autism in their children. They are being told that if they remove these worms with CD (Chlorine Dioxide) treatments the […]

Blogging mother, Temporary Tourist, shares her experiences of Disney’s Guest Assistance rule change

We’ve had mixed responses on Disney’s decision to change the Guest Assistance Card system. We reported Autism Hippie’s experiences on October 11. Disney implemented a change in their guest assistance cards for children and adults with special needs on October 9 after reports that people were flagrantly abusing the old system. Cards called Disability Access […]

About Paul Whiteley Ph.D.

Researcher based in North East England. An academic background in psychology with a special interest in developmental psychology focused specifically on the autism spectrum and related conditions. Postgraduate degrees based on research examining the safety and efficacy of a gluten- and casein-free (GFCF) diet applied to autism and the potential importance of various comorbidity to the health and wellbeing of those on the autism spectrum, with a continuing research interest in these areas. Keen blogger and amateur science writer (but no formal qualifications in these areas). Science is based on probability.